Laredo's Bargain Book: Health And Wellness

Wednesday, February 20, 2019

Health And Wellness

Top Story

Must-Know Health Tips for Faster Flu Recovery

(StatePoint) With last year’s flu season having been associated with 80,000 deaths -- one of the deadliest in decades -- focusing on immune health is important.

Pet Central


Having a pet is a lot of responsibility, and we’ll help by giving you lots of tips and tricks! More >>



Our fitness articles will help teach you how to work out with gym- and home-based exercises. More >>



Enjoy the crosswords challenge in our free daily puzzles, from the harder Sunday crossword to the quicker daily. More >>



Every Sudoku has a unique solution that can be reached logically. Enter numbers into the blank spaces so that each row, column and 3x3 box contains the numbers 1 to 9. More >>

Recent Headlines

Thursday 02/14/2019
4 Benefits of Pet Adoption
Updated: February 18, 2019 - 2:45 am

(Family Features) Pets have an incomparable ability to improve owners’ lives in a number of ways, so it’s only right that pet parents do the same for them. That’s why, if you’re considering adding a pet to the family, adoption can be a great choice.

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5 Ways Dogs Can Improve Lives
Updated: February 18, 2019 - 2:45 am

(Family Features) Whether playmates or protectors, the human-animal bond is often a powerful connection that goes beyond pure companionship. Dogs typically have many talents and personas – they can be man’s best friend, a canine companion during a difficult time or even a service dog helping veterans and others through daily routines. No matter the relationship between dog and human, these animals can improve lives in numerous ways.

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5 Ways to Avoid an Energy Crash
Posted: February 14, 2019

(Family Features) If you start each day motivated but find your energy tends to fade throughout the day, a few simple and easy-to-implement changes to your routine could make all the difference. Minor adjustments to your eating habits, exercise routine and mental attitude can help boost energy levels so you can power through the day feeling fully charged.

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5 Ways Pets Make Life Happier and Healthier
Updated: February 18, 2019 - 2:45 am

(Family Features) More than 84 million U.S. homes have a pet, according to the National Pet Owners Survey, and in many of those homes, pets are a big part of the family. However, there are several barriers that can prevent people from spending time with their furry friends, including outdated housing rules and limited green space in communities.

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A Surprising Solution for Stress Relief
Updated: February 18, 2019 - 2:45 am

(Family Features) From finances and health concerns to lengthy to-do lists, there are numerous sources of strain in the lives of most people.

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3 Tips for a Successful 2019 and Beyond
Updated: February 18, 2019 - 2:46 am

(Family Features) The demands of today’s always-connected culture can make finding balance in life nearly impossible. Between work, school and extracurricular activities, schedules can be crazy, and setting aside time to exercise is often difficult.

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Nicotine to Help Treat Memory Loss?
Updated: February 18, 2019 - 2:46 am

(Family Features) A study funded by the National Institutes of Health is testing whether the nicotine patch can improve memory and functioning in people who have mild memory loss or Mild Cognitive Impairment (MCI).

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Choosing the Right Doctor for You and Your Family
Updated: February 20, 2019 - 2:37 am

(Family Features) What matters to you when finding a doctor to treat you or your family members?

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Cutting Through ‘Wellness Confusion’ to Find Real Weight Loss
Updated: February 20, 2019 - 2:37 am

(Family Features) The secret is out – Americans are no longer in the dark about healthy eating.

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Aiding Aging Parents
Updated: February 20, 2019 - 2:37 am

4 tips to help overcome new challenges

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Wednesday 02/13/2019
4 things you might not know about boat shows
Updated: February 20, 2019 - 2:40 am

(BPT) - Boat shows are taking place across the country, offering opportunities to plan now for warmer days ahead. Special pricing and incentives on new boat models and marine accessories are a major draw for the 142 million Americans who take to the water each year, according to the National Marine Manufacturers Association. For those ready to plan their summer adventures on the water, boat shows are a good place to start.

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What To Do About The Flu
Updated: February 15, 2019 - 2:40 am

(NAPSI)—It’s the peak of flu season, and while fortunately we are not experiencing the epidemic of last year, millions are still suffering from the flu this year. Although common, the flu can be serious and even lead to hospitalization or death. In fact, the Centers for Disease Control and Prevention estimates that in the last seven years the flu has been responsible for more than 700,000 hospitalizations and more than 55,000 deaths across the United States.

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Simplify Your Morning Routine to Get More Out of Your Day
Updated: February 18, 2019 - 2:45 am

(Family Features) Some people wake up each morning refreshed, bright-eyed and ready to take on the day. Others slap the snooze button repeatedly and drag themselves begrudgingly from a cocoon of blankets. Whether you embrace the morning or muddle through, there’s little doubt that those early moments set the stage for the day ahead.

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Easy, On-Demand Dinners
Updated: February 18, 2019 - 2:46 am

(Family Features) Nearly everyone wishes for an extra hour or two in the day. When juggling evenings filled with homework, practices, games and last-minute art projects, even just 60 extra minutes could make the difference in finding time to whip up a dinner you can be proud of. While there’s no changing the fact that there are 24 hours each day, there are some time-saving options for creating family dinners that feel like they’ve come together “on-demand.”

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3 Ways to Make Your Heart Healthier
Updated: February 18, 2019 - 2:46 am

(Family Features) Did you know that heart disease is the leading cause of death in the United States? One in four people die from it each year, according to the Centers for Disease Control and Prevention, and millions more have it or are at risk of developing the disease. Smoking, being overweight or having diabetes, high cholesterol levels, high blood pressure or a family history of heart disease all increase your chances of getting the disease.

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Understanding Insurance Benefits
Updated: February 18, 2019 - 2:46 am

(Family Features) No matter where you are in life, whether you’re just starting your career or nearing retirement, it’s important to understand the voluntary benefits available to you that can complement traditional health insurance.

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Tuesday 02/12/2019
7 ways your community can help your heart health
Posted: February 12, 2019

(BPT) - February is Heart Month — and we don’t mean the romantic kind that we celebrate on Valentine’s Day! Heart Month is time to take stock of your cardiovascular health to combat chronic diseases, like heart disease, which is the number one killer of both men and women in the U.S. The good news is many of the steps you need to take to prevent heart disease are things you can do on your own, just by adopting a few healthy habits. Local communities across the country have been working to make it easier to live healthier through the Healthiest Cities & Counties Challenge (the Challenge).

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What you need to know about Age-related Macular Degeneration.
Updated: February 20, 2019 - 2:37 am

(BPT) - The ability to see the people, places and things in front of you is one of life’s most precious gifts. Imagine a life without the ability to see these things clearly — what steps would you then take to protect your vision? Life with Age-related Macular Degeneration, or AMD, can potentially lead to vision loss or blindness. While an AMD diagnosis can be a scary thought, there are things people can do to help reduce the risk of progression of the disease. Here’s what you need to know.

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How to Save Time, Money and Energy on Household Shopping
Posted: February 12, 2019

(StatePoint) New household products are introduced to store shelves all the time, which can make a typical shopping trip somewhat of a struggle, even for the savviest shoppers.

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Monday 02/11/2019
Facts and tips about protein every expecting and nursing mom should know
Updated: February 20, 2019 - 2:37 am

(BPT) - Eating for two? One critical thing pregnant women and new moms alike need to focus on is maintaining an adequate level of dietary protein, says registered dietitian Melissa Rifkin.

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How Do We Know LASIK Is Safe?
Updated: February 13, 2019 - 2:57 am

(NAPSI)—For those thinking about their vision correction options, the question “Is LASIK safe?” is likely top of mind. To answer, ophthalmologist and chair of the Refractive Surgery Clinical Committee for the American Society of Cataract and Refractive Surgery, John Vukich, M.D., provides hard data:

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Friday 02/08/2019
10 Years and Counting: An Innovative Medicine Helps Patients with a Rare Disease a Decade after its Approval
Updated: February 20, 2019 - 2:38 am

(BPT) - This article is sponsored advertising content from Amgen, Inc.

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Building A Medicaid Bipartisan Bridge
Updated: February 12, 2019 - 2:43 am

by Jeffrey Lewis

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Footballer Jerry Rice Makes Big Play For Kidney Health
Updated: February 12, 2019 - 2:43 am

(NAPSI)—Fans might think Jerry Rice, at 56, should be satisfied to sail silently into the sunset reflecting on his Pro Football Hall of Fame status, three Super Bowl rings, and two decades in the National Football League. Indeed, the iconic wide receiver retired his professional cleats years ago.

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Wednesday 02/06/2019
Thirty Years Of Perfect Harmony To Help Kids
Updated: February 09, 2019 - 2:50 am

by Richard C. Shadyac Jr.

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Transitioning Back to Work After Baby
Updated: February 11, 2019 - 2:58 am

(Family Features) Just when you were getting the hang of having a baby at home, it’s time to go back to work. Beyond the expected changes such as picking work tasks back up and catching up on things you’ve missed, your priorities have most likely shifted now that you’re a parent.

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A Keto-Friendly Approach to Weight Loss
Updated: February 11, 2019 - 2:58 am

(Family Features) A growing number of health-conscious consumers are pursuing a keto lifestyle and products in their pursuit of health benefits, weight loss and improved performance.

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Tuesday 02/05/2019
American Heart Month: Do you know how cholesterol affects your heart?
Updated: February 20, 2019 - 2:37 am

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6 Tips from Doctors for a Healthier Heart
Posted: February 05, 2019

(StatePoint) February is American Heart Month, and an excellent reminder that there are many easy steps you can take to improve your heart health.

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Friday 02/01/2019
A Young Mother's Journey with Major Depressive Disorder
Updated: February 20, 2019 - 2:37 am

(BPT) - “I didn’t realize that depression was more than just sadness.”

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Thursday 01/31/2019
The Onion: Nature's Ninja [Infographic]
Updated: February 20, 2019 - 2:37 am

(BPT) - You know onions are tasty and healthy, but did you know they're also a major action hero? For a healthy heart, mind and gut, learn more about the onion, nature's ninja, and check out for recipe ideas.

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3 Facts About Heart Disease That Might Save Your Life
Updated: February 20, 2019 - 2:37 am

(BPT) - Heart disease is the leading killer of men and women in the U.S. And while we’re frequently reminded about the importance of making healthy choices for prevention, there’s much less attention given to the risk that exists after heart disease diagnosis, including the risk of sudden cardiac death (SCD). In fact, half of all cardiovascular deaths are due to SCD, but that doesn’t have to be the case.[1] If heart disease impacts your family, there are a few things you should know about SCD that could save your life or the life of someone you love.

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Living Better With Chronic Respiratory Diseases
Updated: February 05, 2019 - 2:34 am

(NAPSI)—Here’s news that should help many people with chronic respiratory diseases such as COPD breathe easier: Pulmonary rehabilitation is a proven treatment that improves quality of life.

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Navigating the Obstacles of Disease Treatment
Updated: February 06, 2019 - 2:35 am

(Family Features) A diagnosis of a chronic condition such as Crohn's disease, ulcerative colitis, cancer, or diabetes can bring a swirl of thoughts and emotions. There may be relief at finding an explanation for bothersome symptoms, but that relief is often quickly overshadowed by insurance issues, financial concerns, and worry about the future.

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Wednesday 01/30/2019
In 2019, make sure your child is in the right car seat or seat belt [Infographic]
Updated: February 20, 2019 - 2:38 am

(BPT) - Parents and caregivers want to keep their children safe in the car — but many move their child to the next restraint type too soon. This year, make sure your child always uses the car seat, booster seat or seat belt that is appropriate for their age, height and weight. And remember, children under 13 should always be in the back seat. For more information about choosing the right seat and finding a nearby car seat check location, visit

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Find a Hotel to Fit Your Travel Needs
Updated: February 04, 2019 - 2:31 am

(Family Features) When most people plan a trip, the focus is on the purpose of the journey, whether it’s a work-related jaunt or a vacation with loved ones. Researching and organizing travel for an upcoming trip is important, but so is finding the perfect place to make your journey easier, more productive and successful.

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Make a Difference in Education
Updated: February 04, 2019 - 2:31 am

6 ways to contribute to schools in your community

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Better Yourself in the New Year
Updated: February 04, 2019 - 2:31 am

(Family Features) A new year is the perfect opportunity to take a fresh look at your life and re-evaluate what you’d like to accomplish – both physically and mentally – during the coming year.

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Hug More, Stress Less
Updated: February 04, 2019 - 2:31 am

(Family Features) Whether circumstances are good or bad, exciting or stressful, there are several simple ways to improve emotional and mental fitness.

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5 Steps for Game Day Party Success
Updated: February 04, 2019 - 2:30 am

(Family Features) Whether you have been planning for months or you’re inviting guests the day of, hosting a huge crowd on game day requires a bit more than RSVPs and a welcoming setting. Whether a “huge crowd” to you means five guests or 50, starting out with a plan can help make the day more enjoyable for everyone.

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Tuesday 01/29/2019
Popular diet now offers a keto-friendly program [Video]
Updated: February 20, 2019 - 2:37 am

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Doctor takes the fight against diabetes to the local flea market
Posted: January 29, 2019

(BPT) - In San Juan, Texas, 20 miles from the border of Mexico, diabetes is a serious health problem: One in three people have the disease. With real-time information from modern point-of-care analyzing systems, a team of dedicated professionals led by Dr. Brian Wickwire is doing its best to minimize diabetes’ devastating effects, in a seemingly unlikely spot — the local flea market.

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5 Ways to Choose More Pleasure in Your Life
Updated: February 20, 2019 - 2:38 am

(BPT) - Life is all about making the most of it, every single day. Taking chances, finding new opportunities to explore and pursuing your own unique vision are what make every day a worthwhile adventure. Dove(R) Chocolate is a brand that celebrates women who live boldly and inspire to choose pleasure.

Here are a few ideas of ways you can #choosepleasure.

1. Get in touch with your aspirations. Keep a running list of ideas for things you know you want to do in life, adding to it continually, and then brainstorm concrete steps toward bringing your dreams to life. Don't let anything stand in your way — you can do anything you set your heart on.

2. Schedule more time for what’s important to you. Validate your commitment to doing what you find most satisfying and fulfilling by actually putting those things on your calendar. Being busy with work and play doesn’t have to mean neglecting your own cherished goals and desires. Make the time to pursue the things you know you want to achieve in life — whether it’s starting your own business, writing the book you’ve had in your head or running a marathon. Whatever it is that makes you feel great about your life, schedule it!

3. Take steps toward your goals. Follow what inspires you by taking small steps toward even the biggest goals in your life. If you have a career goal, sign up for a class or workshop in the field to increase your knowledge and expertise. If volunteer work is what inspires you, join a cause or start your own drive to support what you believe in. If you thrive on learning something new, take up the instrument you've always wanted to play, watch online tutorials or enroll in online learning for that language or subject that expands your mind and horizons.

4. Treat yourself boldly. Explore all kinds of new tastes to find treats you absolutely love, and that bring you joy, just like the new Dove(R) Chocolate Bars. Beyond the classic Dark Chocolate and Milk Chocolate varieties, you can try exciting new flavors inspired by the latest culinary trends, from the innovative Bourbon Vanilla Dark Chocolate and Salted Caramel Blonde Chocolate to the sweet and rich Raspberry Rose Dark Chocolate and Almond Brittle Milk Chocolate. Choosing pleasure never tasted so good.

5. Fill your life with great experiences. Your life is an adventure, so don’t wait for it — encourage yourself to make it happen! Get tickets for that concert you really want to attend. Visit that beautiful scenic park with a special friend. Go to that amazing new restaurant or art gallery you’ve been hearing so much about. Be bold and plan that trip to the one place you’ve always wanted to go.

Now is a great time to recommit to your own personal goals and aspirations, whatever they might be. Finding not only your sense of purpose in life, but increasing your sense of satisfaction in daily pleasures makes life so much sweeter. If you want it, go for it! Choose pleasure by centering your life around what you most want and desire.

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Monday 01/28/2019
Addressing Chronic Pain Amidst a National Opioid Crisis
Posted: January 28, 2019

(StatePoint) Chronic pain is among the most prevalent and debilitating medical conditions in the U.S. and opioids are the most commonly prescribed class of medications that are frequently relied on for the management of chronic pain. The high risk for dependence on these drugs and their frequent abuse has results in a national epidemic.

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Friday 01/25/2019
Why Motorcycling May Be the Answer to Lowering Stress Levels
Posted: January 25, 2019

(NewsUSA) - Turns out motorcyclists may get more than a glorious sense of freedom from riding.

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Protecting Your Vision From Diabetes
Updated: February 01, 2019 - 2:34 am

(NAPSI)—Diabetes kills more Americans each year than AIDS and breast cancer combined—and can cause serious problems throughout the body. According to the National Eye Institute, eye health, for example, can become critically compromised.

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Thursday 01/24/2019
Cancer patient has a story to tell about testing
Updated: February 20, 2019 - 2:37 am

(BPT) - For weeks, Nichol Miller had been looking forward to a local 5K obstacle course run. It was September 2014. Her husband Marc and some friends were running the race and Nichol was excited to cheer them on.

Then something happened.

“The next day, I could hardly walk,” said the 45-year-old Oregon mother of three. “My leg was sore and there was a large knot in my thigh. It hurt so badly that I went to my doctor and she sent me to the local hospital for a CT scan.”

Before Nichol left the hospital, she got a call from her doctor, asking her to return to the office.

“I knew from her voice that it wasn’t good. I went back to her office and she told me that it was most likely a tumor,” said Nichol. “When you hear those words, it’s like the floor falls out from under you. Everything was suddenly draped with a cloud of uncertainty.”

Nichol was diagnosed with soft tissue sarcoma. She started chemotherapy and planned to follow treatment with radiation therapy. But after two rounds of chemotherapy, the tumor had grown so large it could not be treated with radiation.

Nichol underwent surgery to remove the tumor in her left hip flexor, and she and Marc hoped the journey was over. Then a new CT scan showed a shadow in Nichol’s lungs. For the second time, the floor fell out from under them.

“At that point, we already knew that chemotherapy wouldn’t work. We did not know what to do,” said Nichol.

Finding answers inside the tumor

Nichol’s doctor had ordered genomic testing on her tumor at the time of her diagnosis. With her cancer growing worse, her doctor re-examined the results, searching for options. They learned from her genomic testing results that her tumor tested positive for a genomic abnormality called a NTRK gene fusion.1

Her doctor searched a clinical trial registry website and found a clinical trial testing a drug that was a match for the genomic makeup of Nichol’s tumor. The closest trial site was in Denver.

Marc and Nichol traveled the 700+ miles from Oregon to Denver. By then, the shadow in Nichol’s lungs had grown so much that it filled about 90 percent of her lungs. She was on oxygen and needed a wheelchair. After she arrived at the hospital, she was treated with antibiotics. Once she recovered, she was eligible to be enrolled in the clinical trial.

The doctors in charge of the clinical trial then started her on the study medication, Vitrakvi® (larotrectinib). Vitrakvi was approved by the U.S. Food and Drug Administration to treat adults and children with solid tumors (cancer) that are caused by certain abnormal NTRK genes, and have spread or if surgery to remove their cancer is likely to cause severe complications, and there is no acceptable treatment option or the cancer grew or spread on other treatment in November 2018.2

Healthcare providers will perform a test to make sure that VITRAKVI is right for you. It is not known if VITRAKVI is safe and effective in children younger than 1 month of age.2

Vitrakvi is approved under accelerated approval based on overall response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in other clinical trials.2

Vitrakvi may cause serious side effects including nervous system problems and liver problems.2 The most common side effects with Vitrakvi include tiredness, nausea, dizziness, vomiting, cough, constipation, diarrhea. Please see more information below; these are not all the possible side effects. Talk to your healthcare provider for more information.2

After each week of treatment, as part of the study protocol, Nichol would go to the clinic every Saturday for blood work.

“As I continued to go to the clinic, my doctors could see that the tumor was shrinking,” said Nichol. “My doctors could see that Vitrakvi was working for me.”

“Nichol is a good example of why testing the makeup of a patient’s tumor is so important. Genomic sequencing identified an alteration in her tumor, and opened the opportunity for her to be in the larotrectinib clinical trial,” said Dr. Lara Davis, Nichol’s oncologist at Oregon Health & Science University. “Although alterations like the one in Nichol’s tumor are uncommon, when one is identified it can make a major and important difference in that individual’s treatment and prognosis.”

Four weeks into the clinical trial, Nichol recalls the thrill of taking her children to the movies and getting to celebrate her birthday.

Nichol has become an advocate for anyone diagnosed with cancer. She wants them to hear this important message:

“Get your tumor genomically tested. Talk to your doctor and ask these two questions: Are there any tests that can be done to show what may be causing my tumor’s growth? And are there any treatments or clinical trials available that are appropriate for my tumor?”

This is the story of one cancer patient’s experience with Vitrakvi® (larotrectinib). Not all patient experiences will be the same.

What is VITRAKVI®?

VITRAKVI (larotrectinib) is a prescription medicine that is used to treat adults and children with solid tumors (cancer) that:

  • are caused by certain abnormal NTRK genes and
  • have spread or if surgery to remove their cancer is likely to cause severe complications, and
  • there is no acceptable treatment option or the cancer grew or spread on other treatment.

Your healthcare provider will perform a test to make sure that VITRAKVI is right for you.

It is not known if VITRAKVI is safe and effective in children younger than 1 month of age.

VITRAKVI is approved under accelerated approval based on overall response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in other clinical trials.

Important Safety Information

VITRAKVI may cause serious side effects, including:

  • Nervous system problems. Tell your healthcare provider if you develop any symptoms such as confusion, difficulty speaking, dizziness, coordination problems, tingling, numbness, or burning sensation in your hands and feet. Your healthcare provider may temporarily stop treatment, decrease your dose, or permanently stop VITRAKVI if you develop symptoms of a nervous system problem with VITRAKVI.
  • Liver problems. Your healthcare provider will do blood tests to check your liver function during treatment with VITRAKVI. Tell your healthcare provider right away if you develop symptoms of liver problems including: loss of appetite, nausea or vomiting, or pain on the upper right side of your stomach area. Your healthcare provider may temporarily stop treatment, decrease your dose, or permanently stop VITRAKVI if you develop liver problems with VITRAKVI.

Before taking VITRAKVI, tell your healthcare provider about all of your medical conditions, including if you:

  • have liver problems
  • have nervous system (neurological) problems
  • are pregnant or plan to become pregnant. VITRAKVI can harm your unborn baby. You should not become pregnant during treatment with VITRAKVI.
    • If you are able to become pregnant, your healthcare provider may do a pregnancy test before you start treatment with VITRAKVI.
    • Females who are able to become pregnant should use effective birth control (contraception) during treatment and for at least 1 week after the final dose of VITRAKVI. Talk to your healthcare provider about birth control methods that may be right for you.
    • Males with female partners who are able to become pregnant should use effective birth control during treatment with VITRAKVI and for at least 1 week after the final dose of VITRAKVI.
  • are breastfeeding or plan to breastfeed. It is not known if VITRAKVI passes into your breast milk. Do not breastfeed during treatment and for 1 week after the last dose of VITRAKVI
  • VITRAKVI may affect fertility in females and may affect your ability to become pregnant. Talk to your healthcare provider if this is a concern for you.

While on VITRAKVI, you should avoid:

  • driving or operating machinery until you know how VITRAKVI affects you. VITRAKVI can make you feel dizzy.
  • taking St. John’s wort, eating grapefruit, or drinking grapefruit juice during treatment with VITRAKVI.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter (OTC) medicines, vitamins, and herbal supplements. Certain other medicines may affect how VITRAKVI works.

The most common side effects with VITRAKVI include:

  • Tiredness
  • Nausea
  • Dizziness
  • Vomiting
  • Cough
  • Constipation
  • Diarrhea

These are not all the possible side effects with VITRAKVI. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

For full prescribing information, visit:


  1. Amatu A, Sartore-Bianchi A, Siena S. ESMO Open. 2016;1(2):e000023.
  2. Vitrakvi® (larotrectinib) capsules and solution for oral use [Patient Prescribing Information]. Stamford, CT: Loxo Oncology Inc.; November 2018.

© 2018 Bayer. Bayer, the Bayer Cross and Vitrakvi are registered trademarks of Bayer.



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What You Need To Know About Cholesterol
Updated: January 26, 2019 - 2:36 am

(NAPSI)—New cholesterol guidelines from the American Heart Association emphasize a personalized approach to preventing and treating high cholesterol and cardiovascular disease.

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How One Volunteer is Helping End a Family Cycle of Alzheimer’s
Posted: January 24, 2019

(StatePoint) Jacqueline Patterson, 66, knew from a young age what Alzheimer’s looked like, but didn’t call it by its name until she started caring for her mother, Ruby, in 2008.

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